Treatments for Kidney Disease
Treatments focus on slowing the progression of the disease. One that helps is Filspari, a prescription medication used to treat a rare kidney condition called IgA nephropathy (IgAN).
Filspari
Filspari (sparsentan) is a prescription medication used to treat a rare kidney condition called IgA nephropathy (IgAN). Filspari works by blocking two receptors (endothelin and angiotensin) that are involved in causing high blood pressure and kidney damage.
Filspari works by targeting two key receptors–endothelin and angiotensin–which are involved in kidney damage and high blood pressure. By blocking these receptors, protein levels in the urine are reduced. High protein levels in urine often signal kidney damage, so reducing this can help slow the disease’s progression.
Common side effects can include headaches, dizziness and fatigue, though many patients find it manageable with proper dosing and care. It’s essential for patients to have regular monitoring to manage blood pressure and kidney function effectively.
Common Treatment Options
1. Medications
- Blood pressure medications: Since high blood pressure often accompanies kidney disease, medications such as ACE inhibitors and ARBs are commonly used. These drugs help lower blood pressure and reduce protein in urine, which can slow kidney damage.
- Diuretics: Diuretics help reduce fluid buildup in the body and lower blood pressure by promoting urine production. They are particularly useful for patients with advanced kidney disease who experience swelling.
- Erythropoiesis-Stimulating Agents (ESAs): Kidney disease often leads to anemia due to reduced erythropoietin production. ESAs stimulate red blood cell production to alleviate symptoms of anemia, such as fatigue.
2. Diet and Lifestyle Modifications
Diet plays a crucial role in managing kidney disease, as it helps reduce the strain on kidneys.
- Low-sodium diet: Follow a kidney-friendly diet. Limiting salt intake. Dietary changes may include limiting protein, eating foods that reduce blood cholesterol levels and limiting sodium and potassium intake. These changes can help control blood pressure and reduces fluid buildup
- Protein restriction: Too much protein can increase waste in the blood, which overburdens kidneys. A low-protein diet can help reduce kidney stress.
- Limit potassium and phosphorus: People with kidney disease often need to control potassium and phosphorus intake to avoid complications.
- Exercise and movement: Regularly exercising and being active can make a huge difference in not only your kidney health but your body’s overall health. This also includes making sure to stay at a weight that’s healthy for you.
3. Dialysis
For those with advanced kidney disease or kidney failure, dialysis may be necessary. Dialysis mechanically filters waste from the blood, helping to manage symptoms when kidneys can no longer perform effectively.
- Hemodialysis: This form of dialysis uses a machine to filter blood through an external device.
- Peritoneal dialysis: A less invasive approach, where the peritoneal membrane in the abdomen filters waste internally.
4. Kidney Transplant
For patients with end-stage kidney disease, a kidney transplant can be a life-saving procedure. A successful transplant requires a compatible kidney from a donor, which could be challenging due to long wait times and limited availability.
When to Consult Your Doctor
If you’re diagnosed with kidney disease, regular check-ups and monitoring are vital for early intervention and treatment adjustments. Reach out to your healthcare provider if you notice:
- Persistent swelling in your legs, feet or hands.
- Uncontrolled blood pressure despite medication.
- Fatigue or weakness that doesn’t improve.
- Changes in urination frequency or color.
Read on to learn about the risk factors for kidney cancer.