Treatments for Gastrointestinal Stromal Tumors (GISTs)
Managing these tumors with effective treatments can help reduce symptoms. Consider QINLOCK (ripretinib), a medication designed to treat GISTs by targeting enzymes that promote tumor growth.
QINLOCK (Ripretinib)
QINLOCK is a newer medication designed to slow down the growth of GISTs, particularly for cases where other treatments have not been successful. It works by targeting specific enzymes that help the tumor grow. Doctors often turn to QINLOCK when the tumor keeps growing despite other treatments. By controlling the tumor’s activity, QINLOCK can help ease symptoms and improve quality of life.
Surgery
Surgery is often the first line of treatment, especially if the tumor is small and in a location where it can be safely removed. During surgery, doctors aim to extract as much of the tumor as possible. Surgery works best for GISTs that have not yet spread to other parts of the body, as removing the tumor can effectively stop its growth and ease symptoms.
Imatinib (Gleevec)
Imatinib is a targeted therapy that blocks specific proteins in the body to prevent the tumor from growing. It’s commonly used as the initial treatment option for GISTs. Many patients experience positive results with Imatinib, as it can keep the tumor under control for extended periods.
Sunitinib (Sutent)
Sunitinib targets multiple proteins involved in cell growth and works to halt tumor growth. This treatment is typically recommended when Imatinib is no longer effective or if the tumor recurs. For some, Sunitinib provides a secondary option to manage and control tumor progression when other medications don’t work.
Regorafenib (Stivarga)
Regorafenib is another targeted therapy that blocks different pathways in the body to suppress tumor growth. It’s often used as a follow-up treatment when Imatinib and Sunitinib are not effective. Regorafenib provides another option for controlling GISTs that continue to grow despite previous therapies.
What to Expect During Treatment
Every treatment affects people differently, and side effects can vary. Common experiences with these medications include fatigue, nausea and potential changes in blood counts. Some patients may also feel discomfort or changes in appetite. Your healthcare team will closely monitor these effects and can adjust the treatment if needed to ensure comfort and effectiveness.
Each of these treatments, including newer options like QINLOCK, offers hope for managing GISTs. Working with a medical team that understands the latest treatment options can help ensure the best care and potentially improve life with GISTs.
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